Research Article

Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats

Table 4

Spasmolytic effect of aqueous and ethanolic stem bark extracts of Nauclea diderrichii on normal motility.

TreatmentsDose (mg/kg)Total length of intestine (cm)Traveled distance by charcoal (cm)Peristaltic index (%)% inhibition

Distilled water1 ml/100 g
DMSO (5%)1 ml/100 g
Atropine sulfate131.08
Aqueous extract10011.94
20031.07
30031.67
Ethanolic extract100a24.32
200bb32.70
300aa26.40