[Retracted] Cell-in-Cell: From Cell Biology to Translational Medicine

Figure 1

The mechanisms and its biological significance of homotypic CICs. Homotypic CICs are formed by three core machineries, including intact adherens junctions (AJs), imbalance of contractile actomyosin (CA) of invading cells, and the mechanical ring (MR). Homotypic CICs play important roles in tumor evolution, genomic instability, and tumor aggressive.