Research Article
rs12329760 Polymorphism in Transmembrane Serine Protease 2 Gene and Risk of Coronavirus Disease 2019 Mortality
Table 3
TMPRSS2 rs12329760 association with COVID-19 mortality.
| | Groups | | | Model | Genotype | Improved patients () | Dead patients () | OR (95% CI) | value | AIC | BIC |
| | Allele | C | 871 (63.0%) | 1096 (93.0%) | — | — | — | — | | T | 515 (37.0%) | 88 (0.7%) | — | — | — | — |
| | Codominant | C/C | 270 (39.0%) | 513 (86.7%) | 1.00 | <0.0001 | 1448.8 | 1469.5 | | C/T | 331 (47.8%) | 70 (11.8%) | 0.11 (0.08-0.15) | | T/T | 92 (13.3%) | 9 (1.5%) | 0.05 (0.03-0.10) |
| | Dominant | C/C | 270 (39.0%) | 513 (86.7%) | 1.00 | <0.0001 | 1451.8 | 1467.3 | | C/T-T/T | 423 (61.0%) | 79 (13.3%) | 0.10 (0.07-0.13) |
| | Recessive | C/C-C/T | 601 (86.7%) | 583 (98.5%) | 1.00 | <0.0001 | 1707.3 | 1722.8 | | T/T | 92 (13.3%) | 9 (1.5%) | 0.10 (0.05-0.20) |
| | Overdominant | C/C-T/T | 362 (52.2%) | 552 (88.2%) | 1.00 | <0.0001 | 1573.5 | 1598.0 | | C/T | 331 (47.8%) | 70 (11.8%) | 0.15 (0.11-0.20) |
| | Minor allele frequency (T) | 0.37 | 0.07 | — | — | — | — |
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OR: odds ratios; CI: confidence intervals; AIC: Akaike information criterion; BIC: Bayesian information criterion.
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