Research Article

rs12329760 Polymorphism in Transmembrane Serine Protease 2 Gene and Risk of Coronavirus Disease 2019 Mortality

Table 4

Factors associated with dead patients infected with COVID-19.

Factors
Baseline predictorsOR (95% CI) value

Mean 0.975 (0.958-0.993)0.006
HDL (mg/dL)1.046 (1.025-1.066)<0.001
LDL (mg/dL)1.024 (1.019-1.030)<0.001
Uric acid (mg/dL)2.043 (1.768-2.361)<0.001
Creatinine (mg/dL)0.074 (0.038-0.145)<0.001
ESR (mm/1st h)0.965 (0.951-0.979)<0.001
CRP (mg/L)0.973 (0.963-0.984)0.004
25-hydroxyvitamin D (ng/ml)1.057 (1.038-1.077)<0.001
AST (IU/L)0.983 (0.973-0.992)<0.001
Real-time PCR Ct values0.961 (0.932-0.991)0.011
TMPRSS2 rs12329760 (CC)16.723 (10.841-25.798)<0.001

HDL: high-density lipoprotein; LDL: low-density lipoprotein; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; AST: aspartate aminotransferase; Ct: cycle threshold; TMPRSS2: transmembrane protease 2; SD: standard deviation; OR: odds ratios; CI: confidence intervals; Statistically significant (<0.05).