Investigating the Mechanism of Rhizoma Coptidis-Eupatorium fortunei Medicine in the Treatment of Type 2 Diabetes Based on Network Pharmacology and Molecular Docking

Table 1

Effective chemical components of R-E in the treatment of T2DM.

Effective chemistry component code	Molecular name	OB (%)	DL	Drug source
MOL001454	Berberine	36.86	0.78	Rhizoma Coptidis
MOL013352	Obacunone	43.29	0.77	Rhizoma Coptidis
MOL002894	Berberrubine	35.74	0.73	Rhizoma Coptidis
MOL002897	Epiberberine	43.09	0.78	Rhizoma Coptidis
MOL002903	(R)-Canadine	55.37	0.77	Rhizoma Coptidis
MOL002904	Berlambine	36.68	0.82	Rhizoma Coptidis
MOL002907	Corchoroside A_qt	104.95	0.78	Rhizoma Coptidis
MOL000622	Magnograndiolide	63.71	0.19	Rhizoma Coptidis
MOL000762	Palmidin A	35.36	0.65	Rhizoma Coptidis
MOL000785	Palmatine	64.60	0.65	Rhizoma Coptidis
MOL000098	Quercetin	46.43	0.28	Rhizoma Coptidis
MOL001458	Coptisine	30.67	0.86	Rhizoma Coptidis
MOL002668	Worenine	45.83	0.87	Rhizoma Coptidis
MOL008647	Moupinamide	86.71	0.26	Rhizoma Coptidis
MOL000006	Luteolin	36.16	0.25	Eupatorium fortunei
MOL000359	Sitosterol	36.91	0.75	Eupatorium fortunei
MOL000363	Amyrin palmitate	32.68	0.30	Eupatorium fortunei
MOL000449	Stigmasterol	43.83	0.76	Eupatorium fortunei
MOL000584	7-Acetoxy-8-hydroxy-9-isobutyryloxythymol	33.39	0.18	Eupatorium fortunei
MOL000588	9-Acetoxy-8,10-epoxy-6-hydroxythymol 3-O-angelate	61.44	0.21	Eupatorium fortunei
MOL000592	Dammaradienyl acetate	46.52	0.82	Eupatorium fortunei
MOL000595	Eupatoriopicrin	76.78	0.36	Eupatorium fortunei
MOL000596	[(3S,4aR,6aR,6aR,6bR,8aR,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,12,14b-Heptamethyl-11-methylene-1,2,3,4a,5,6,6a,7,8,9,10,12,12a,13,14,14a-hexadecahydropicen-3-yl] acetate	43.08	0.74	Eupatorium fortunei
MOL000604	Eupaformosanin	50.20	0.52	Eupatorium fortunei
MOL000605	Taraxasterol palmitate	33.84	0.31	Eupatorium fortunei