Investigating the Mechanism of Rhizoma Coptidis-Eupatorium fortunei Medicine in the Treatment of Type 2 Diabetes Based on Network Pharmacology and Molecular Docking

Table 2

Molecular docking results of core targets and key active ingredients.

Hub targets	Quercetin (kcal/mol)	Luteolin (kcal/mol)	Berberine (kcal/mol)	Palmatine (kcal/mol)	Coptisine (kcal/mol)
ESR1	-4.99	-4.82	-7.72	-8.05	-8.33
MAPK1	-5.35	-5.20	-8.14	-8.04	-8.25
AKT1	-6.37	-6.54	-8.72	-8.28	-8.95
TP53	-4.04	-4.52	-6.35	-6.26	-6.59
IL6	-6.48	-6.37	-8.39	-8.07	-8.53
JUN	-4.45	-4.90	-9.22	-8.78	-9.58