Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway

Table 1

SCD1 status and its association with clinicopathological characteristics in CRC patients.

SCD1 expression
Characteristics	Number	High	(%)	Low	(%)
Gender
Male	299	203	67.90%	96	32.10%	0.15
Female	192	142	73.90%	50	26.10%
Age (years)
≤50	64	41	64.10%	23	35.90%	0.24
>50	427	304	71.20%	123	28.80%
Location
Right side colon	112	76	67.80%	36	32.10%	0.53
Left side colon	93	58	62.40%	35	37.60%
Rectum	286	211	73.80%	75	26.20%
Mucin production
With	46	40	86.90%	6	13.10%	0.07
Without	425	305	71.76%	120	28.20%
Tumor differentiation
Poor	106	68	64.20%	38	35.80%	0.12
Moderate/well	385	277	71.90%	108	28.10%
Tumor diameter
≤ 5 cm	269	190	70.60%	79	29.40%	0.85
>5 cm	222	155	69.80%	67	30.20%
Tumor stage
	288	191	66.30%	97	33.70%	0.02
III	203	154	75.90%	49	24.10%
Bowel wall invasion (T)
	91	62	68.10%	29	31.90%	0.62
	400	283	70.80%	117	29.20%
Lymph node metastasis ()
Without	288	191	66.30%	97	33.70%	0.02
With	203	154	75.90%	49	24.10%
Lymphovascular invasion
No	335	244	72.80%	91	27.20%	0.07
Yes	156	101	64.70%	55	35.30%
Alcohol intake
Never	387	275	71.10%	112	28.90%	0.46
Ever	104	70	67.30%	34	32.70%
Smoking
Ever	137	87	63.50%	50	36.50%	0.043
Never	354	258	72.90%	96	27.10%
Cancer family history
Yes	93	68	73.10%	25	26.90%	0.25
No	119	95	79.80%	24	20.20%
Unknown	279
Colorectal family history
Yes	29	18	62.10%	11	37.90%	0.047
No	183	144	78.70%	39	21.30%
Unknown	279
MSI status
MSI	68	46	67.60%	22	32.40%	0.61
MSS	423	299	70.70%	124	29.30%
KRAS status
Mutation	212	147	69.30%	65	30.70%	0.7
Wild type	279	198	70.90%	81	29.10%