Gut Microbiome Characteristics in Mothers and Infants According to the Presence of Atopic Dermatitis
Table 1
Demographic and clinical characteristics of the total study population.
Variable
Healthy controls (100)
AD (100)
value
Infant
Male gender, (%)
7 (77.8)
2 (33.3)
0.136
Parental allergic diseases, (%)
6 (66.6)
6 (100)
0.229
Administration of antibiotics, (%)
5 (55.5)
5 (83.3)
0.580
<3 months
0
0
3–5 months
2
2
≥6 months
3
3
Breast-feeding or mixed feeding, (%)
1.000
≤6 months
7 (77.7)
4 (66.6)
>6 months
2 (22.3)
2 (33.4)
Presence of sibling (yes), (%)
5 (55.5)
5 (83.3)
0.580
Onset time of AD, (%)
≤6 months
NA
3 (50.0)
>6 months
NA
3 (50.0)
SCORAD of 12 months
NA
13.5 ± 7.17
Severity of AD at 12 months, (%)
Mild (<25)
NA
5 (83.3)
Moderate (25 ≤ and ≤50) and severe (>50)
NA
1 (16.7)
Skin prick test result, (%)
NA
3 (50.0)
Egg, (%)
NA
2 (33.3)
HDM, (%)
NA
1 (16.7)
Mother
Mean age
0.236
Allergic diseases, (%)
2 (22.2)
4 (66.6)
0.136
Antibiotics treatment in pregnancy, (%)
0
2 (33.3)
0.143
Diet in pregnancy, n (%)
0.608
Vegetarian or Korea traditional diet
5 (55.5)
2 (33.3)
Meat or instant diet
4 (44.5)
4 (66.7)
Values are presented as number (%) and mean ± standard error. AD, allergic dermatitis; NA, not applicable; SCORAD, scoring of atopic dermatitis. HDM, house dust mite. Mann–Whitney test.
