The Link between ANRIL Gene RS4977574 Polymorphism and Common Atherosclerosis Cardiovascular Complications: A Hospital-Based Case-Control Study in Ukrainian Population
Table 4
Analysis of ANRIL rs4977574 genotypic association with the risk of atherosclerosis complications.
Model
(95% CI)
(95% CI)
Atherosclerosis (common group)
AG+GG vs AA
0.044
1.436 (1.009-2.044)
0.185
1.286 (0.887-1.866)
GG vs AA+AG
0.025
1.551 (1.058-2.273)
0.048
1.501 (1.003-2.246)
AG vs AA+GG
0.872
0.974 (0.704-1.347)
0.600
0.912 (0.645-1.288)
Large artery stroke
AG+GG vs AA
0.097
1.423 (0.938-2.159)
0.258
1.283 (0.833-1.974)
GG vs AA+AG
0.140
1.396 (0.896-2.176)
0.123
1.435 (0.907-2.270)
AG vs AA+GG
0.791
1.053 (0.721-1.537)
0.771
0.943 (0.634-1.402)
Acute coronary syndrome
AG+GG vs AA
0.084
1.450 (0.952-2.209)
0.214
1.351 (0.840-2.171)
GG vs AA+AG
0.015
1.719 (1.110-2.660)
0.049
1.648 (1.002-2.711)
AG vs AA+GG
0.582
0.898 (0.613-1.317)
0.554
0.876 (0.565-1.358)
Note: 95% CI: 95% confidence interval; : observed value (unadjusted for covariates); : observed odds ratio; : value adjusted for sex, age, body mass index, smoking habit, and arterial hypertension; : odds ratio after adjusting for covariates.