Research Article

The Link between ANRIL Gene RS4977574 Polymorphism and Common Atherosclerosis Cardiovascular Complications: A Hospital-Based Case-Control Study in Ukrainian Population

Table 4

Analysis of ANRIL rs4977574 genotypic association with the risk of atherosclerosis complications.

Model (95% CI) (95% CI)

Atherosclerosis (common group)
AG+GG vs AA0.0441.436 (1.009-2.044)0.1851.286 (0.887-1.866)
GG vs AA+AG0.0251.551 (1.058-2.273)0.0481.501 (1.003-2.246)
AG vs AA+GG0.8720.974 (0.704-1.347)0.6000.912 (0.645-1.288)

Large artery stroke
AG+GG vs AA0.0971.423 (0.938-2.159)0.2581.283 (0.833-1.974)
GG vs AA+AG0.1401.396 (0.896-2.176)0.1231.435 (0.907-2.270)
AG vs AA+GG0.7911.053 (0.721-1.537)0.7710.943 (0.634-1.402)

Acute coronary syndrome
AG+GG vs AA0.0841.450 (0.952-2.209)0.2141.351 (0.840-2.171)
GG vs AA+AG0.0151.719 (1.110-2.660)0.0491.648 (1.002-2.711)
AG vs AA+GG0.5820.898 (0.613-1.317)0.5540.876 (0.565-1.358)

Note: 95% CI: 95% confidence interval; : observed value (unadjusted for covariates); : observed odds ratio; : value adjusted for sex, age, body mass index, smoking habit, and arterial hypertension; : odds ratio after adjusting for covariates.