Research Article

[Retracted] Prognosis and Therapeutic Efficacy Prediction of Adrenocortical Carcinoma Based on a Necroptosis-Associated Gene Signature

Figure 2

LASSO Cox regression selected necroptosis-associated genes with the best optimal lambda value, the association between NAGs and clinical features, and the survival analysis among NAGs groups. (a) The coefficients of 49 necroptosis-associated genes. (b) The seven necroptosis-associated genes selected with the best optimal lambda value, including LEF1, MAPK8, CYLD, TRAF2, DNMT1, PLK1, and GATA3. (c) The negative correlation between NAGs and OS in ACC. (d) Distribution of clinicopathological, status of survival, and tumor stage among NAGs groups. (e) Predictive accuracy of necroptosis-related gene signature at 1 year, 3 years, and 5 years, and the accuracy was equal to the corresponding AUC value. (f) Two distinct subgroups divided by the mean NAGs. (g) Different survival probabilities between the two defined subgroups are showed in K-M curves.
(a)
(b)
(c)
(d)
(e)
(f)
(g)