Suppressive, Curative, and Prophylactic Effects of Maesa lanceolata Forssk. against Rodent Malaria Parasite Plasmodium berghei

Table 6

Body weight and temperature of malaria-infected study animals treated with M. lanceolata 80% methanol leaf extract in Rane’s study.

Test substances	Dose/day	Body weight (g)			Rectal temperature (°C)
		D3	D7	% change	D3	D7	% change
PW	10 ml/kg			−14.27			−13.05
ML	200 mg/kg			−12.49^b^e			−11.46^b^e
	400 mg/kg			−9.91^b			−8.00^a^b
	600 mg/kg			−5.36^a			−4.11^a
CQ	25 mg/kg			−1.04^a			−0.64^a

Values are designated as (); ^a compared to PW, ^b to CQ 25 mg, and ^e 600 mg of ML: , , ; PW: pure water (negative control); ML: crude extract of M. lanceolata; CQ: chloroquine. D3: values (pretreatment) on day 4; D7: values (posttreatment) on day 8.