Suppressive, Curative, and Prophylactic Effects of Maesa lanceolata Forssk. against Rodent Malaria Parasite Plasmodium berghei

Table 9

Hematocrit of malaria-infected study mice treated with M. lanceolata methanolic (80%) leaf extract in the chemoprophylactic test.

Test substances	Dose/day	Packed cell volume
		D4	D7	% change
PW	10 ml/kg			−6.86
ML	200 mg/kg			−5.04^b
	400 mg/kg			−4.07
	600 mg/kg			−2.86
CQ	25 mg/kg			0.41^a

Values are designated as (); ^a compared to PW, ^b to CQ 25 mg,: , ; PW: pure water (negative control); ML: 80% methanol extract of M. lanceolata; CQ: chloroquine; D4: preinfection values on day 5; D7: postinfection values on day 8.