Research Article

Bushen Huoxue Formula Modulates Autophagic Flux and Inhibits Apoptosis to Protect Nucleus Pulposus Cells by Restoring the AMPK/SIRT1 Pathway

Figure 6

The AMPK/SIRT1 pathway engages in autophagy activation. (a–m) The indicators of AMPK, p-AMPK, and SIRT-1 were measured by western blotting. The dorsomorphin was used to intervene with the cells fostered with TNF-α and BSHXF. The group treated with serum containing BSHXF, and ; the TNF-α group, # and ##; the dorsomorphin-treated group, and ∆∆.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)
(i)
(j)
(k)
(l)
(m)