Research Article

Solidified Reverse Micellar Solution- (SRMS-) Based Microparticles for Enhanced Oral Bioavailability and Systemic Antifungal Efficacy of Miconazole Nitrate in Immunocompromised Mice

Table 4

Pharmacokinetic parameters of formulations.

Formulation (μg/mL) (hr)AUC (μg/hr/mL)AUMC (μg/mL/hr2) (hr) (mL)Clearance (mL/kg/hr)MRT (hr)

Batch
Batch
Batch
MN powder

MN: miconazole nitrate; Batch : 5% LM1, containing 3% MN; Batch : 5% LM2 containing 3% MN; Batch : 5% LM3 containing 3% MN (values presented as the , ).