Research Article
Preoperative CD52 Level Predicts Graft Survival following Kidney Transplantation
Table 2
Univariate and multivariate analyses of preoperative and postoperative factors affecting graft loss.
| Variables | Comparison | (%) | Univariate | Multivariate | HR (95% CI) | value | HR (95% CI) | value |
| Age | ≥50 | 56 (58%) | 1.406 (0.582–3.395) | 0.449 | | | <50 | 40 (42%) | | |
| Gender | Male | 62 (64.5%) | 0.849 (0.346–2.085) | 0.721 | | | Female | 34 (35.5%) | | |
| Serum creatinine (6 months after KTx) | 0.7–6 | | 1.908 (1.192–3.053) | 0.007 | 1.700 (1.022–2.828) | 0.041 |
| Acute allograft rejection | Yes | 17 (17.7%) | 2.997 (1.239–7.250) | 0.015 | 2.919 (1.118–7.623) | 0.029 | No | 79 (82.3%) |
| DGF | Yes | 20 (20.8%) | 2.672 (1.113–6.412) | 0.028 | 1.361 (0.500–3.706) | 0.546 | No | 76 (79.2%) |
| Total HLA mismatch | ≤2 | 34 (35.4%) | 1.169 (0.868–1.576) | 0.304 | | | >2 | 62 (64.6%) | | |
| BK virus infection | Yes | 17 (17.7%) | 2.673 (0.856–8.348) | 0.091 | 0.988 (0.224–4.366) | 0.987 | No | 79 (82.3%) |
| Serum levels of CD52 | CD52 ≥260 pg/mL | 39 (40.6%) | 3.168 (1.346–7.454) | 0.008 | 3.114 (1.026–9.604) | 0.045 | CD52 <260 pg/mL | 57 (59.4%) |
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DGF: delayed graft function; HLA: human leukocyte antigen; KTx: kidney transplantation.
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