miRNA-Gene Interaction Network Construction Strategy to Discern Promising Traditional Chinese Medicine against Osteoporosis

Figure 1

Identification of osteoporosis-associated miRNAs. (a) Hierarchical clustering tree and the module colors were plotted to display the modules. (b) The correlations between the 5 modules and osteoporosis. (c) The correlation between module membership and gene significance in the turquoise module. (d) The differentially expressed miRNAs were screened out in 18 osteoporosis and 12 healthy cases with the cutoff criteria adjusted  value < 0.01 and . (e) Venn diagram displayed the shared miRNAs between 132 differentially expressed miRNAs and 55 miRNAs in the turquoise module.

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