Studying the Anticancer Effects of Thymoquinone on Breast Cancer Cells through Natural Killer Cell Activity

Figure 1

NK cell cytotoxicity against MCF-7 cells in the presence or absence of thymoquinone. Fifty μM of thymoquinone upregulated NK cell cytotoxicity in MCF-7 cells significantly compared to the control cells (NK + TC) at P < 0.04 (one-way ANOVA, Tukey’s test). Cell cytotoxicity significantly increased in TC + TQ25 + NK and TC + TQ50 + NK compared to TC25 and TC + TQ50 at P < 0.0064 and P < 0.0251, respectively (one-way ANOVA, Tukey’s test). There was a significant increase in NK cell cytotoxicity between the two doses of thymoquinone (25 and 50 μM) at P < 0.04 (one-way ANOVA, Tukey’s test). All data are expressed as mean ± SD of three independent experiments.