Preliminary Study of Gastroprotective Effect of Aloe perryi and Date Palm Extracts on Pyloric Ligation-Induced Gastric Ulcer in Experimental Rats

Table 6

Histological lesion scores for gastric alterations depending on loss of the mucosal and glandular layers, edema, and congested blood vessels with control and treatment doses and types.

Lesion	Control	Ranitidine	APLE		APFE		DPSE		Yellow oil		Red oil
			250	500	250	500	250	500	250	500	250	500
Denudation of the mucosal parts	3	1	3	2	0.5	2	3	2	3	2	2	0
Congested blood vessels	3	0	3	1	1	1	3	1	3	1	1	0
Inflammatory cell infiltrations	3	0	2	1	2	1	2	1	2	1	1	0
Loss of the mucosal and glandular layers	3	0.5	3	2	1	2	3	2	3	2	2	0
Mucosal and/or submucosal edema	3	1	3	2	2	2	3	1	2	2	2	0
Regenerated tissues	0	2	1	2	1	2	1	1	0	1	1	3
Return to nearly normal feature	0	2	0	0	0	0	0	0	0	0	0	3

Control: rats received only distilled water; APLE: rats received the Aloe perryi leaf extract in a dose level (500 mg/kg) (p.o.); ranitidine: rats received ranitidine which is dissolved in distilled water and given in a dose level (50 mg/kg) (p.o.) and served as a standard drug; APFE: rats received the Aloe perryi flower extract in a dose level (500 mg/kg) (p.o.); DPSE: rats received the date palm seed extract in a dose level (500 mg/kg) (p.o.); yellow oil group: rats received date yellow oil in a dose level (500 mg/kg) (p.o.); red oil group: rats received date red oil in a dose level (500 mg/kg) (p.o.). The lesion scores: 0 = normal appearance; 0.5 = mild changes; 1 = moderate changes; 1.5 = severe changes; 2 = over severity; and 3 = diffused.