The Oxidative Drug Combination for Suppressing KRAS G12D Inducible Tumour Growth

Figure 2

ATO titration and cell death in AK 192 cell line. (a) Morphological changes in AK 192 cells after 24 h of increased dose of ATO. (b) Representative histograms of % of PI positive cells in control (GM) and after treatment with increased dose of ATO at 24 and 48 h. (c) Bar chart of % of dead cells in each condition at 24 and 48 h. (d) Histograms of % of PI positive cells in GM after combined treatment with ATO 5uM and D-VC 1 mM. (e) Bar chart of % of dead cells in GM and after combined treatment with ATO 5μM and D-VC 1 mM at 24 and 48 h.

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