The Oxidative Drug Combination for Suppressing KRAS G12D Inducible Tumour Growth

Figure 4

Flow cytometric analysis of mitochondrial ROS production in AK 192 cells under treatment conditions. (a) Histograms with % of MitoSox positive cells (gate set up on unstained sample) for conditions treated with PBS (GM), 5μM ATO, 1 mM D-VC, combination of 5uM ATO and 1 mM D-VC, combination of 5uM ATO and 1 mM D-VC and 5 mM NAC A. (b) analysis of MitoSox was done in triplicates and the average values are show on a bar chart.

(a)

(b)