Research Article
Association of Interleukin-1 Beta and Interleukin-1 Receptor Antagonist Gene Polymorphisms and Plasma Levels with Diabetic Nephropathy
Table 2
Hardy-Weinberg equilibrium test for the genotype distributions of IL-1β (-511C/T), IL-1β (+3953C/T), and IL-1Ra (+8006C/T) in the DN and HC groups.
| | Genotype | Group | | Genotype (%) | | | TT | TC | CC |
| | IL-1β (-511C/T) | DN | Measured | 61 | 46 (75.4) | 11 (18.0) | 4 (6.6) | | | Theoretical | 44 (71.0) | 16 (25.8) | 2 (3.2) | | | HC | Measured | 48 | 22 (45.8) | 19 (39.6) | 7 (14.6) | | | Theoretical | 21 (42.9) | 22 (44.9) | 6 (12.2) | | | IL-1β (+3953C/T) | DN | Measured | 61 | 16 (26.2) | 24 (39.3) | 21 (34.4) | | | Theoretical | 13 (21.3) | 30 (49.2) | 18 (29.5) | | | HC | Measured | 48 | 16 (33.3) | 12 (25.0) | 20 (41.7) | | | Theoretical | 10 (20.8) | 24 (50.0) | 14 (29.2) | | | IL-1Ra (+8006C/T) | DN | Measured | 61 | 1 (1.6) | 10 (16.4) | 50 (82.0) | | | Theoretical | 1 (1.6) | 11 (17.7) | 50 (80.6) | | | HC | Measured | 48 | 1 (2.1) | 8 (16.7) | 39 (81.2) | | | Theoretical | 1 (2.0) | 9 (18.4) | 39 (79.6) | |
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