Circadian Clock Genes Act as Diagnostic and Prognostic Biomarkers of Glioma: Clinic Implications for Chronotherapy

<div>Correlation between the four key CCGs and drug sensitivity. (a) Positive correlation represents that the drug is resistant to high expression of the gene, and vice versa. (b) The drug sensitivity curve of temozolomide varied with the rhythm of <i>ARNTL</i> expression.</div>

BioMed Research International

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Figure 11

Figure 11: Circadian Clock Genes Act as Diagnostic and Prognostic Biomarkers of Glioma: Clinic Implications for Chronotherapy 