Circadian Clock Genes Act as Diagnostic and Prognostic Biomarkers of Glioma: Clinic Implications for Chronotherapy

Figure 4

Correlations of DNA methylation, CNV, and SNP with CCGs. (a) Correlation between methylation and CCGs’ mRNA expression. The size of the point represents the statistical significance, where the bigger the dot size, the higher the statistical significance. (b) Correlation of CNV with CCGs’ mRNA expression. The size of the point represents the statistical significance, where the bigger the dot size, the higher the statistical significance. (c) SNP mutation frequency of CCGs in Pan cancer. (d) Graph of genes regulated by CNV and methylation. FDR: false discovery rate; cor: correlation.

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