Identification of MAD2L1 as a Potential Biomarker in Hepatocellular Carcinoma via Comprehensive Bioinformatics Analysis

Table 2

Univariate and multivariate survival analyses.

Characteristics	OS
	Univariate			Multivariate
	HR	95% CI	value	HR	95% CI	value
MAD2L1expression	11.511	(3.471-38.110)	<0.001	8.644	(2.543-29.382)	0.001
Low vs. high
Age (years)	0.721	(0.352-1.476)	0.371
≤50 vs. >50
Gender	0.520	(0.124-2.176)	0.371
Male vs. female
AJCC stage	2.262	(1.128-4.536)	0.021	1.230	(0.599-2.527)	0.512
I vs. II-III
HBsAg	1.001	(0.429-2.336)	0.998
Negative vs. positive
AFP (ng/mL)	0.888	(0.434-1.818)	0.746
≤400 vs. >400
Total bilirubin (μmol/L)	1.113	(0.428-2.893)	0.826
≤20 vs. >20
ALT (U/L)	0.935	(0.457-1.912)	0.853
≤45 vs. >45
GGT (U/L)	0.386	(0.159-0.937)	0.035	0.572	(0.231-1.416)	0.227
≤40 vs. >40
Edmondson-Steiner grade	5.198	(2.384-11.336)	<0.001	3.640	(1.589-8.333)	0.002
I-II vs. III-IV
Tumor number	1.810	(0.742-4.417)	0.192
Single vs. multiple
Tumor size (cm)	0.504	(0.250-1.018)	0.056
≤5 vs. >5