Systematic Review on Multilevel Analysis of Radiation Effects on Bone Microarchitecture

Table 4

Methodology of reviewed studies.

Citation	Rodents’ strain and sample size ()	Radiation dose	Modalities used	Timing of data collection post irradiation
Limirio et al., [15]	Wistar rats	30 Gy	(1) μCT; (2) Mechanical testing	Day 30 and 60
Bartlow et al., [16]	BALB/cJ	20 Gy	(1) μCT; (2) Fracture toughness testing	Weeks 0, 4, 8, and 12
Wright et al., [17]	C57Bl/6	2 Gy	μCT	Day 7
Barbosa et al., [18]	NZ rabbits	30 Gy	(1) μCT; (2) Mechanical testing	Day 1, 7, 14, 21, and 28
Oest et al., [19]	BALB/cJ		(1) μCT; (2) Mechanical testing	Weeks 0, 1, 2, 4, 8, 12, and 26
Sullivan et al., [20]	C57BL/6		(1) μCT; (2) Mechanical testing	Day 35
Lima et al., [21]	BALB/cBYJ	0.17 Gy, 0.5 Gy, and 1 Gy	μCT	Day 3 or 21
Zhai et al., [22]	Male Sprague-Dawley rats	2 Gy and	μCT	3, 7, 14, 30, and 60 days