Prognostic Bone Metastasis-Associated Immune-Related Genes Regulated by Transcription Factors in Mesothelioma

Figure 8

Immune regulatory network and ATAC-seq validation. (a) Integrated network includingSDC2 and 4 TFs, 11 immune cells, and 10 pathways; (b) gene loci on different chromosomes; (c) intersection of different pick types (genic, intergenic, exon, upstream, intron, and distal intergenic); (d) distribution of binding loci relative to TSS; (e) correlation analysis of TCF7L1 and SDC2 (, ); (f) in ATAC-seq data of MESO samples, multiple binding peaks were identified in SDC2 and TCF7L1 sequences.

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