Traditional Chinese Medicine Compound Preparations Are Associated with Low Disease-Related Complication Rates in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study of 11,074 Patients

Table 2

Changes in the rheumatoid arthritis-related inflammatory and immune indices after administration of TCMCP ().

	Before treatment	After treatment		value	Reference ranges
ESR (median (Q1, Q3), mm/h)	48.0 (29.00, 70.00)	28.00 (16.00, 44.00)	-34.498	<0.001	2-6
CRP (median (Q1, Q3), mg/L)	24.29 (7.00, 50.57)	2.00 (0.48, 8.66)	-40.240	<0.001	0-5
IgA (median (Q1, Q3), g/L)	2.65 (2.00, 3.48)	2.48 (1.91, 3.22)	-15.313	<0.001	0.7-4.06
IgG (median (Q1, Q3), g/L)	12.98 (10.07, 16.70)	12.00 (9.56, 15.30)	-18.241	<0.001	6.8-14.5
IgM (median (Q1, Q3), g/L)	1.26 (0.89, 1.66)	1.28 (0.91, 1.72)	-3.983	<0.001	0.3-2.2
C3 (median (Q1, Q3), g/L)	110.60 (87.70, 129.90)	100.20 (81.70, 115.10)	-23.671	<0.001	75-135
C4 (median (Q1, Q3), g/L)	23.50 (15.6, 30.10)	19.30 (12.60, 24.90)	-27.145	<0.001	9-36
Anti-CCP (median (Q1, Q3), mmol/L)	240.90 (105.92, 473.98)	220.45 (84.15, 452.69)	-6.170	<0.001	<25
RF (median (Q1, Q3), U/mL)	101.70 (33.55, 244.50)	88.85 (27.53, 216.45)	-20.372	<0.001	0-14

Note: TCMCP: traditional Chinese medicine compound preparation; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; IgA: immunoglobulin A; IgM: immunoglobulin M; IgG: immunoglobulin G; C3: complement C3; C4: complement C4; anti-CCP: anti-cyclic citrullinated peptide; RF: rheumatoid factor. is the standardized test statistics before and after treatment of TCMCP. The value is compared before and after treatment with TCMCP.