An Immunogenic Cell Death-Related Gene Signature Reflects Immune Landscape and Predicts Prognosis in Melanoma Independently of BRAF V600E Status

Figure 2

Identification of ICD-related subgroups using consensus clustering in BRAF V600E WT SKCM cohort. (a) Heatmap depicts consensus clustering solution () for 34 genes in 470 SKCM samples. (b) Cumulative distribution function (CDF) curve for . (c) Delta area curve of consensus clustering indicates the relative change in area under the cumulative distribution function (CDF) curve for to 10. (d) Heatmap of 34 ICD-related gene expressions in cluster C1 and cluster C2. Red represents high expression and blue represents low expression. (e) The Kaplan-Meier survival curve analysis reveals that the OS rate of patients in ICD-high group is higher than those in ICD-low group.

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