Cell Cycle-Related Gene SPC24: A Novel Potential Diagnostic and Prognostic Biomarker for Laryngeal Squamous Cell Cancer

Table 3

Univariate and multivariate Cox regression analysis of SPC24 clinical pathologic features according to the TCGA database.

Parameters OS	Univariate analysis				Multivariate analysis
	HR	Lower_95%	Upper_95%	value	HR	Lower_95%	Upper_95%	value
vs. ≥60	-0.14	0.47	1.6	0.66	0.29	0.15	0.57	0.0004
Gender female vs. male	-1.2	0.15	0.59	0.0005
Clinical stage I/II vs. III/IV					0.36	0.16	0.78	0.01
Smoking 1 vs. 2	0.33	0.12	0.9	0.03	0.4	0.15	1.12	0.08
Smoking 1 vs. 3	0.15	0.04	0.55	0.005	0.2	0.05	0.78	0.02
Smoking 1 vs. 4	0.31	0.11	0.89	0.029	0.44	0.15	1.29	0.13
SPC24 expression low vs. high	-0.41	0.44	0.99	0.044	0.33	0.16	0.69	0.003