Research Article

In Silico Characterization of an Important Metacyclogenesis Marker in Leishmania donovani, HASPB1, as a Potential Vaccine Candidate

Table 2

The final screening of shared linear B-cell epitopes from the LdHASPB1 protein.

Shared B-cell epitopesVaxiJen antigenicity scoreAllerTOP allergenicity predictionPepCalc water solubility prediction

KEDGHTQKNDG1.3843YesWeak
TQKNDGDG1.5354NoGood
KEDGHTQK1.2394NoGood
PQKRADN0.5911NoWeak
AQEKNEDGHNVGD1.1338NoGood
IHKTTEANH0.2796YesGood
PKEDGHTQK1.2709NoWeak
GDGPKEGENLQ1.2153NoGood

Potent shared antigenic and allergenic linear B-cell epitopes with good water solubility.