Structural Dynamics of P-Rex1 Complexed with Natural Leads Establishes the Protein as an Attractive Target for Therapeutics to Suppress Cancer Metastasis

Table 1

GOLD fitness score and binding energy of the two hits and control.

Hit	Compound 3D structure	Gold fitness score	AutoDock Vina binding energy in kcal/mol
Top-1		82.5	-12.8
Top-2		82.1	-12.6
Control		75.14	-11.7