Transcriptomic Network Regulation of Rat Tooth Germ from Bell Differentiation Stage to Secretory Stage: MAPK Signaling Pathway Is Crucial to Extracellular Matrix Remodeling

<div>Mandibular molar germ and its histological morphology. (a) There was no obvious mineralized tissue in the P1.5 tooth germ under the microscope, and there were small apex protrusions. (b) Microscopically, tooth germ of P3.5 had obvious mineralized dental cusp tissue, and the mineralized layer was thin. (c, d) H&amp;E staining of global and local structures of mandibular molar germ in P1.5 (up) and P3.5 (down). With the development of germ, the mineralized structure gradually widened. Am: ameloblast; En: enamel; De: dentin; PreDe: predentin; Od: odontoblast; Dp: dental papilla.</div>

BioMed Research International

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Figure 1

Figure 1: Transcriptomic Network Regulation of Rat Tooth Germ from Bell Differentiation Stage to Secretory Stage: MAPK Signaling Pathway Is Crucial to Extracellular Matrix Remodeling 

Figure 1 | Transcriptomic Network Regulation of Rat Tooth Germ from Bell Differentiation Stage to Secretory Stage: MAPK Signaling Pathway Is Crucial to Extracellular Matrix Remodeling 