Whole-Transcriptome Sequencing Combined with High-Dimensional Proteomic Technologies Reveals the Potential Value of miR-135b-5p as a Biomarker for Hepatocellular Carcinoma

Figure 5

Differential expression of immune pathways, immune cells, and ICI therapy-related gene signatures between the miR-135b-5p-high and miR-135b-5p-low groups. (a) Heatmap shows the expression of seven immune pathway-related gene signatures in the miR-135b-5p-high and miR-135b-5p-low groups. (b) Heatmap shows the expression of 11 immune cell-related gene signatures in the miR-135b-5p-high and miR-135b-5p-low groups. (c) Heatmap shows the expression of three anti-PD-1 therapy-related gene signatures in the miR-135b-5p-high and miR-135b-5p-low groups. (d) Representative IMC images show the expression of PD-L1 in the miR-135b-5p-high (left) and miR-135b-5p-low groups (middle); box plot shows the expression of PD-L1 in the miR-135b-5p-high and miR-135b-5p-low groups (right). , , , and . ns: no significance.

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