The Prevalence and Determinants of Inappropriate Oral Anticoagulant Use in Patients with Atrial Fibrillation, in Resource-Limited Setting
Table 5
Binary logistic regression for predictive factors towards inappropriate anticoagulation management practice among AF patients at the Yekatit 12 Hospital Medical College from November 2019 to March 2020, Addis Ababa, Ethiopia.
Variable
Appropriate vs inappropriate anticoagulation, (%)
Crude OR (CI 95%)
Adjusted OR (CI 95%)
value
Types of AF
Valvular
22
76
1.00
Nonvalvular
99
34
0.352 (0.247-0.519)
0.488 (0.651-0.982)
0.004
CHA2DS2-VASc score
1
9
1
1.00
2
44
13
1.948 (0.620-1.185)
1.753 (0.418-2.238)
≥3
46
20
8.473 (0.199-10.32)
1.638 (0.399-6.719)
Chronic valvular heart disease
Yes
107
6
1.00
No
124
9
8.188 (0.968-7.407)
9.109 (0.503-6.866)
Hypertension
Yes
64
5
1.00
No
167
7
8.386 (3.143-8.292)
10.36 (0.346-2.639)
Diabetes mellitus
Yes
29
2
1.00
No
202
3
7.651 (0.635-5.809)
3.363 (0.754-6.547)
Chronic kidney disease
Yes
15
1
1.00
No
216
2
3.139 (0.754-5.505)
4.299 (0.565-3.103)
Stroke
Yes
6
2
1.00
No
225
4
0.175 (0.374-4.221)
1.95 (0.794-6.529)
Congestive heart disease
Yes
82
24
1.00
No
149
35
0.36 (4.795-11.47)
0.146 (4.803-7.541)
0.002
Hyperthyroidism
Yes
38
1
1.00
No
193
4
8.473 (0.969-6.282)
1.638 (0.339-7.371)
Degenerative valvular heart disease
Yes
25
2
1.00
No
206
3
1.01 (0.704-4.340)
0.961 (0.545-2.078)
Type and method of anticoagulation
No anticoagulant
0
88
1.00
Warfarin
102
0
0.316 (0.293-2.812)
0.939 (0.933-6.584)
Aspirin
10
22
0.85 (0.682-1.804)
0.614 (0.551-1.902)
Both warfarin and aspirin
9
0
0.266 (0.923-1.911)
0.57 (0.263-3.142)
Statistically significant association with inappropriate anticoagulation management practice.
