Evaluation of Systemic Genotoxic/Oxidative and Proinflammatory Effects in Workers of a Titanium Dioxide Production Plant

Table 6

Fpg-comet results: comet percentages, apoptotic cells, and oxidative DNA damage analysed taking into account the specific task.

Markers/task		Mean	SD	value	Multiple comparisons
% comets
Bagging operators	4	18.88	1.26	0.026 (ANOVA)	Post hoc (Bonferroni test)	value
Industrial cleaners	5	21.56	2.65
Mobile operators	9	19.26	0.65
Maintainers	13	19.61	1.05		Industrial cleaners < control	0.013
Technicians	9	19.97	1.94
Office workers	5	19.00	0.35
External controls	18	18.86	1.55
% apoptotic cells
Bagging operators	4	0.85	0.39	0.129 (ANOVA)
Industrial cleaners	5	0.76	0.65
Mobile operators	9	0.64	0.23
Maintainers	13	1.03	0.44
Technicians	9	0.96	0.42
Office workers	5	0.70	0.16
External controls	18	0.65	0.36
Oxidative DNA damage
Bagging operators	4	4.10	0.55	0.361 (Kruskal-Wallis)
Industrial cleaners	5	3.48	4.00
Mobile operators	9	2.98	1.38
Maintainers	13	2.75	4.25
Technicians	9	4.12	3.91
Office workers	5	5.01	2.24
External controls	18	2.47	1.60
Oxidative positive subjects > cutoff 4
Bagging operators	2/4 (50%)			0.493 (Fisher’s exact test)
Industrial cleaners	1/5 (20%)
Mobile operators	2/9 (22.2%)
Maintainers	7/13 (53.8%)
Technicians	2/9 (22.2%)
Office workers	2/5 (40%)
External controls	4/18 (22.2%)