Doxycycline as a Potential MMP-1 Inhibitor for the Treatment of Spondylitis Tuberculosis: A Study in Rabbit Model

Figure 2

X-ray images of rabbits after 4-week incubation (a) without treatment, showing marked sclerotic changes, damaged vertebral bodies, and adjacent structures, compared with rabbits treated with doxycycline at (b) 1 mg/kg BW and (c) 5 mg/kg BW.

(a)

(b)

(c)