Doxycycline as a Potential MMP-1 Inhibitor for the Treatment of Spondylitis Tuberculosis: A Study in Rabbit Model

Table 5

MMP-1 serum levels and immunohistochemical examinations for spondylitis TB.

Group	Blood levels of MMP-1			Immunohistochemistry of MMP-1
	Before	After	value	Positive	Negative
A	0.309	0.531	0.048	4	2
B	0.298	0.373	0.251	3	3
C	0.287	0.193	0.062	2	4
D	0.398	0.439	0.352	2	4
E	0.389	0.211	0.116	1	5
F	0.406	0.117	0.024	1	5
G	0.521	0.269	0.079	1	5
H	0.511	0.139	0.037	1	5
I	0.526	0.121	0.027	1	5
J	0.462	0.131	0.037	0	6
K	0.421	0.116	0.041	0	6
L	0.457	0.091	0.033	0	6

value between before and after treatment with doxycycline for 4 weeks.