Research Article

The Effect of Different Luteal Phase Support Applications on Clinical Pregnancy Outcomes in Frozen-Thawed Embryo Transfer

Table 2

Different treatment groups’ demographic data and treatment results.

All age groups
TotalVaginal P4 gelOral P4 tbP4 IM
()()()()

Age (year) median (min/max)33 (20/45)31 (22/45)34 (26/41)33 (20/44)0.287k
BMI (kg/m2) median (min/max)24.23 (17.3/40)23.55 (17.3/40)23.55 (19.5/29.3)25 (18/38.25)0.234k
The cause of infertility (%)0.245ff
 Male46 (28)14 (24.6)10 (33.3)22 (28.6)
 Female75 (45.7)30 (52.6)10 (33.3)35 (45.5)
 Male and female25 (15.2)5 (8.8)5 (16.7)15 (19.5)
 Unknown18 (11)8 (14)5 (16.7)5 (6.5)
Pregnancy (%)92 (56.1)24 (42.1)17 (56.7)51 (66.2)a0.021c
Endometrium (mm) median (min/max)10.2 (7/22)10 (7/15.4)11.1 (8/14)10 (7/22)0.174k
Number of attempts () median (min/max)1 (1/8)1 (1/8)1 (1/4)1 (1/6)0.635k
FSH (mlU/ml) median (min/max)7.43 (2.35/23.77)7.49 (2.69/22.6)7.3 (4.61/18.2)6.94 (2.35/23.77)0.671k
LH(IU/l) median (min/max)5.46 (0.42/14.9)5 (1.12/13.52)b6.72 (0.51/14.9)5.21 (0.42/12.6)b0.001k
AMH (ng/ml) median (min/max)1.96 (0.01/15)1.9 (0.14/12.66)1.96 (0.07/15)2.05 (0.01/12.95)0.907k
TSH (milliliter) median (min/max)1.87 (0.12/6.03)1.88 (0.3/6.03)1.86 (0.19/3.26)1.9 (0.12/4.74)0.785k
E2 (pg/ml) median (min/max)
 Basal41.23 (12/97.27)41.2 (12/97.27)45.15 (24.5/86.7)39.59 (12.68/79)0.129k
 Transfer354.5 (105.4/979)354 (105.4/879.62)353 (145/768)356 (115/979)0.827k
 Difference (transfer-basal)310.9 (44.59/951.1)315.6 (68.66/851.62)296.95 (104.2/717.2)318.5 (44.59/951.1)0.817k
value for basal vs. transfer<0.001ᵚ<0.001ᵚ<0.001ᵚ<0.001ᵚ
Progesterone (ng/ml) median (min/max)
 Basal0.63 (0.14/1.76)0.53 (0.14/1.51)0.73 (0.26/1.04)0.64 (0.21/1.76)0.056k
 Transfer14.35 (1.28/80)9.56 (3.13/78)16.05 (5.4/60)16.12 (1.28/80)0.107k
 Difference (transfer-basal)13.72 (0.8/78.69)9.22 (2.49/77.7)15.27 (4.84/59.24)15.68 (0.8/78.69)0.119k
value for basal vs. transfer<0.001ᵚ<0.001ᵚ<0.001ᵚ<0.001ᵚ

kKruskal-Wallis H test (Monte Carlo); Post hoc test: Dunn's test; ffFisher-Freeman-Halton test (Monte Carlo); cPearson's chi-square test (Monte Carlo); Wilcoxon test (Monte Carlo); aexpresses significance according to Crinone, bexpresses significance according to Duphaston; min: minimum; max: maximum.