Antimalarial Efficacy and Safety of Senna occidentalis (L.) Link Root Extract in Plasmodium berghei-Infected BALB/c Mice

Table 1

Plasmodium berghei parasitemia and parasite suppression levels (%) in BALB/c mice following treatment with Senna occidentalis methanolic root extract.

Treatment type	Parasitemia (%) on day 4 postinfection	Parasitemia (%) on day 8 postinfection	Suppression (%) on day 8 postinfection
A	4.81 ± 0.42	22.96 ± 4.51	54.15
B	4.88 ± 0.29	22.87 ± 5.53	54.33
C	5.15 ± 0.19	0.17 ± 0.00	99.67
D	5.23 ± 0.31	50.08 ± 3.41	0

A: infected and given methanolic extract (100 mg/kg); B: infected and given methanolic extract (200 mg/kg); C: infected and given pyrimethamine; D: infected and given PBS (vehicle).