Antimalarial Efficacy and Safety of Senna occidentalis (L.) Link Root Extract in Plasmodium berghei-Infected BALB/c Mice

Table 3

White blood cell indices in Plasmodium berghei-infected and uninfected BALB/c mice administered with Senna occidentalis methanolic root extract.

White blood cell parameters	Experimental groups
	A	B	C	D	E	F
WBC (×10^9/l)	15.85 ± 2.25^(p^)	6.55 ± 1.15^(p^)	3.45 ± 0.65^(p^)	28.85 ± 1.65	8.2 ± 0.8	5.95 ± 0.75
LYM (%)	88.9 ± 0.1	87.05 ± 1.55	92.9 ± 0.5	81.1 ± 5.6	84.1 ± 0.6	86.5 ± 3.05
GRAN (%)	4.75 ± 0.15	7.5 ± 1.8	3.05 ± 0.85	8.9 ± 2.1	7.35 ± 0.65	6.3 ± 2.3

^(p)Statistically significant change; A: infected and given methanolic extract (100 mg/kg); B: infected and given methanolic extract (200 mg/kg); C: infected and given pyrimethamine; D: infected and given PBS; E: not infected but given extract (200 mg/kg); F: not infected but given PBS.