Antimalarial Efficacy and Safety of Senna occidentalis (L.) Link Root Extract in Plasmodium berghei-Infected BALB/c Mice

Table 5

Platelet indices in Plasmodium berghei-infected and uninfected BALB/c mice administered with Senna occidentalis methanolic root extract.

Platelet indices	Experimental groups
	A	B	C	D	E	F
PLT (×10^9/l)	338.5 ± 9.5	335 ± 17.5	375.5 ± 17.5	341 ± 22	419 ± 33	451.5 ± 31.5
MPV (ft)	6.55 ± 0.05	7.7 ± 0.5	7.25 ± 1.15	7.8 ± 0.3	6.75 ± 0.05	6.2 ± 0.1
PDW (%)	8.6 ± 0.2	9.05 ± 1.05	9.5 ± 0.3	8.25 ± 0.15	9.55 ± 0.25	8.3 ± 0

A: infected and given methanolic extract (100 mg/kg); B: infected and given methanolic extract (200 mg/kg); C: infected and given pyrimethamine; D: infected and given PBS; E: not infected but given extract (200 mg/kg); F: not infected but given PBS.