Association between RIT2 rs16976358 Polymorphism and Autism Spectrum Disorder in Asian Populations: A Meta-analysis

Table 4

Meta-analysis of rs16976358 polymorphism and risk of ASD in Asian populations. -test and are applied to assess the heterogeneity. -test was used for evaluating value. If , the fixed-effect model was adopted to calculate the pooled ORs; if , the random-effect model was applied instead.

Genetic models			Random model (95% CI)		Fixed model (95% CI)
Allele C vs. T	0.110	85.6%			1.767 (1.517-2.057)	0.001
Codominant CC vs. TT	0.840	72.9%			4.402 (2.630-7.369)	0.001
Codominant CT vs. TT	0.031	92.4%	1.614 (1.127-2.311)	0.009
Dominant CC+CT vs. TT	0.034	92.1%	1.781 (1.270-2.498)	0.001
Recessive CC vs. CT+TT	0.849	72.9%			3.700 (2.217-6.176)	0.001
Over dominant TT+CC vs. CT	0.057	90.8%	0.663 (0.479-0.916)	0.013