Investigation on the Mechanisms of Zanthoxylum bungeanum for Treating Diabetes Mellitus Based on Network Pharmacology, Molecular Docking, and Experiment Verification

Table 3

The results of molecular docking.

Compound	Target	PDB	Libdock score
Kokusaginin	AKT1	1 h10	40.36
Skimmianin	AKT1	1 h10	26.46
Diosmetin	AKT1	1 h10	56.65
Beta-sitosterol	AKT1	1 h10	67.85
Quercetin	AKT1	1 h10	56.04
Kokusaginin	IL6	1alu	66.33
Skimmianin	IL6	1alu	77.02
Diosmetin	IL6	1alu	79.18
Beta-sitosterol	IL6	1alu	70.68
Quercetin	IL6	1alu	71.44
Kokusaginin	HSP90AA1	1byq	88.68
Skimmianin	HSP90AA1	1byq	73.36
Diosmetin	HSP90AA1	1byq	91.09
Beta-sitosterol	HSP90AA1	1byq	0
Quercetin	HSP90AA1	1byq	89.96
Kokusaginin	FOS	1a02	93.34
Skimmianin	FOS	1a02	87.24
Diosmetin	FOS	1a02	105.47
Beta-sitosterol	FOS	1a02	118.17
Quercetin	FOS	1a02	107.43
Kokusaginin	JUN	1jnm	98.24
Skimmianin	JUN	1jnm	0
Diosmetin	JUN	1jnm	120.99
Beta-sitosterol	JUN	1jnm	125.09
Quercetin	JUN	1jnm	104.87