Identification of Genetic Variants for Diabetic Retinopathy Risk Applying Exome Sequencing in Extreme Phenotypes

Table 3

Total number of rare missense variants (<1% in gnomAD) which were observed in at least two subjects, either in cases or controls, and which had in silico aggregate prediction of pathogenicity.

Cases	Controls	Pearson’s chi-squared test
202	302	0.00035