Research Article

Identifying G6PC3 as a Potential Key Molecule in Hypoxic Glucose Metabolism of Glioblastoma Derived from the Depiction of 18F-Fluoromisonidazole and 18F-Fluorodeoxyglucose Positron Emission Tomography

Figure 2

Relationship between glucose metabolism-related molecule mRNA levels and fluorine-18-fluorodeoxyglucose (18F-FDG) uptake lesion-to-normal brain ratio (LNR). (a) Glucose transporter 1 (GLUT1) mRNA levels did not correlate with 18F-FDG LNR (). (b, c) Hexokinase 2 and glucose-6-phosphatase catalytic unit 3 mRNA levels significantly correlated with FDG LNR (, , and , , , respectively). These were tested by Spearman’s rank correlation coefficient.
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