Identifying G6PC3 as a Potential Key Molecule in Hypoxic Glucose Metabolism of Glioblastoma Derived from the Depiction of ¹⁸F-Fluoromisonidazole and ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography

Figure 5

The significance of G6PC3 mRNA expression on the prognosis. (a) In another cohort in our institute, G6PC3 mRNA expression was significantly different between the two groups. Higher G6PC3 mRNA expression was observed in the poor prognosis group than in the good prognosis group (good prognosis: median 0.88, ; poor prognosis: median 1.40, ; , Mann–Whitney test). (b) In The Cancer Genome Atlas database, two groups were stratified according to a threshold of the median G6PC3 mRNA expression. Patients with higher G6PC3 mRNA expression (, median 385.0 days, 95% C.I. 0.46–0.91) had poorer overall survival than those with lower mRNA expression (, median 455.0 days, 95% C.I. 1.11–2.18) by log-rank test (). 95% confidence interval: 95% C.I.

(a)

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