In Silico Identification of a Potential TNF-Alpha Binder Using a Structural Similarity: A Potential Drug Repurposing Approach to the Management of Alzheimer’s Disease

Table 4

Pharmacokinetic properties of the 10 DrugBank compounds.

Drug	BBB permeant	GI absorption
Metoserpate (DB11530)	Yes	High
Deserpidine (DB01089)	No	High
18-Methoxycoronaridine (DB15096)	Yes	High
CP-320626 (DB03383)	No	High
Rescinnamine (DB01180)	No	High
Reserpine (DB00206)	No	High
Raubasine (DB15949)	Yes	High
Methoserpidine (DB13631)	No	High
(7as,12ar,12bs)-1,2,3,4,7a,12,12a,12b-Octahydroindolo[2,3-a]Quinolizin-7(6h)-One (DB02191)	Yes	High
Vinburnine (DB13793)	Yes	High

BBB = blood brain-barrier; GI = gastrointestinal.