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Behavioural Neurology
Volume 11 (1998), Issue 2, Pages 113-116
Case report

Late-Onset Startle Syndrome and Obsessive Compulsive Disorder

Alejandro Gonzalez and Michael P. Philpot

Maudsley Hospital, London, UK

Received 1 August 1998; Accepted 1 August 1998

Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A case of late onset sporadic startle syndrome in a patient with a right posterior fossa brain tumour is reported. The exaggerated startle response did not respond to treatment with clonazepam. In addition to anxiety and depression, the patient developed obsessive- compulsive symptoms which responded to behavioural therapy. The possible mechanisms for this unique pattern of symptoms are discussed.