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Behavioural Neurology
Volume 12, Issue 3, Pages 119-125

The Processing of Global and Local Visual Information in Alzheimer’s Disease

Eriko Matsumoto,1 Yoshitaka Ohigashi,1 Misato Fujimori,2 and Etsuro Mori2

1Department of Graduated school of human and environmental studies, Kyoto University, Japan
2Divisions of Clinical Neurosciences and Neuroimaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan

Received 7 December 2000; Accepted 7 December 2000

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We examined the quantitative and qualitative difference of the pattern with visuo-cognitive processing impairment in patients with early onset AD (EOAD) and late onset AD (LOAD). We use a visual attention task introduced by Navon (1977) to examine the function to integrate local visual stimuli into global image. Although the ability to identify solid digits ether of large and small size presented at the same exposure duration, EOAD performance was poor in the global perception especially at the short duration (20~msec). We provide evidence that this dysfunction is attribute to the AD pathology specific to early onset type.