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Behavioural Neurology
Volume 14, Issue 3-4, Pages 103-107

Cognitive and Emotional Dysfunction after Central Pontine Myelinolysis

Tatia M. C. Lee,1,2,3 Crystal C. Y. Cheung,1,2 Esther Y. Y. Lau,1 Amanda Mak,2 and Leonard S. W. Li2,3

1Neuropsychology Laboratory, The University of Hong Kong, Hong Kong
2Institute of Clinical Neuropsychology, The University of Hong Kong and MacLehose Medical Rehabilitation Centre, Hong Kong
3Department of Medicine, The University of Hong Kong, Hong Kong

Received 16 December 2003; Accepted 16 December 2003

Copyright © 2003 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The case of a 67-year-old right-handed Chinese man with Central Pontine Myelinolysis [CPM] is described to illustrate the resulting cognitive and emotional disturbances. A comparison of the data in this report with that in published studies suggests that ethnicity does not seem to have much effect on the symptoms of CPM. Possible underlying neural-pathological mechanisms are discussed. This case further substantiates the speculation that the brainstem plays a role in higher cognitive processes and emotional regulation.